Dual binding site inhibitors of B-RAF kinase

Dual binding site inhibitors of B-RAF kinase Structure-based design of isoindoline-1,3-diones and 2,3-dihydrophthalazine-1,4-diones as novel B-Raf inhibitors Design and Synthesis of Orally Bioavailable Benzimidazoles as Raf Kinase Inhibitors Design and synthesis of isoquinolines and benzimidazoles as RAF kinase inhibitors Application of a novel [3+2] cycloaddition reaction to prepare substituted imidazoles and their use in the design of potent DFG-out allosteric B-Raf inhibitors Design, synthesis, and biological evaluation of new B-RafV600E kinase inhibitors Novel Inhibitors of B-RAF Based on a Disubstituted Pyrazine Scaffold. Generation of a Nanomolar Lead Probing a 3,4′-bis-guanidinium diaryl derivative as an allosteric inhibitor of the Ras pathway Conformation-Specific Effects of Raf Kinase Inhibitors Pyridoimidazolones as Novel Potent Inhibitors of v-Raf Murine Sarcoma Viral Oncogene Homologue B1 (BRAF)