Synthesis of all stereoisomers of KRN7000, the CD1d-binding NKT cell ligand

Synthesis of all stereoisomers of KRN7000, the CD1d-binding NKT cell ligand Syntheses and biological activities of KRN7000 analogues having aromatic residues in the acyl and backbone chains with varying stereochemistry Synthesis and Biological Activities of 5-Thio-α-GalCers Syntheses of Biotinylated α-Galactosylceramides and Their Effects on the Immune System and CD1 Molecules Synthesis and Th1-immunostimulatory activity of α-galactosylceramide analogues bearing a halogen-containing or selenium-containing acyl chain RCAI-133, an N-methylated analogue of KRN7000, activates mouse natural killer T cells to produce Th2-biased cytokines RCAI-17, 22, 24–26, 29, 31, 34–36, 38–40, and 88, the analogs of KRN7000 with a sulfonamide linkage: Their synthesis and bioactivity for mouse natural killer T cells to produce Th2-biased cytokines α-S-GalCer: Synthesis and evaluation for iNKT cell stimulation RCAI-84, 91, and 105-108, ureido and thioureido analogs of KRN7000: Their synthesis and bioactivity for mouse lymphocytes to produce Th1-biased cytokines Synthesis and evaluation of 3″- and 4″-deoxy and -fluoro analogs of the immunostimulatory glycolipid, KRN7000