α-S-GalCer: Synthesis and evaluation for iNKT cell stimulation

Bioorganic & Medicinal Chemistry Letters
2008.0

Abstract

The synthesis and evaluation for iNKT stimulation of alpha-S-galactosylceramide is reported. Prepared by alkylation of a galactosylthiol, this analog of the potent immunostimulatory agent, KRN7000, did not stimulate iNKT cells either in vitro or in vivo.

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