Novel potent and selective Ca2+ release-activated Ca2+ (CRAC) channel inhibitors. Part 3: Synthesis and CRAC channel inhibitory activity of 4′-[(trifluoromethyl)pyrazol-1-yl]carboxanilides

Novel potent and selective Ca2+ release-activated Ca2+ (CRAC) channel inhibitors. Part 3: Synthesis and CRAC channel inhibitory activity of 4′-[(trifluoromethyl)pyrazol-1-yl]carboxanilides Discovery of a Novel Potent and Selective Calcium Release-Activated Calcium Channel Inhibitor: 2,6-Difluoro-N-(2′-methyl-3′-(4-methyl-5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)-[1,1′-biphenyl]-4-yl)benzamide. Structure–Activity Relationship and Preclinical Characterization Initial SAR studies on apamin-displacing 2-aminothiazole blockers of calcium-activated small conductance potassium channels Synthesis and Activity against Multidrug Resistance in Chinese Hamster Ovary Cells of New Acridone-4-carboxamides Discovery of 7-azaindole derivatives as potent Orai inhibitors showing efficacy in a preclinical model of asthma SAR of a Series of 5,6-Dihydro-(9H)-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-α]pyridines as Potent Inhibitors of Human Eosinophil Phosphodiesterase 3,4-Dihydroquinazoline derivatives as novel selective T-type Ca2+ channel blockers Novel calcium antagonists. Synthesis and structure-activity relationship studies of benzothiazoline derivatives Synthesis and biological activity of 3,4-dihydroquinazolines for selective T-type Ca2+ channel blockers Synthesis and biological evaluation of novel T-type calcium channel blockers