Focus on the Controversial Activation of Human iNKT Cells by 4-Deoxy Analogue of KRN7000

Focus on the Controversial Activation of Human iNKT Cells by 4-Deoxy Analogue of KRN7000 α-S-GalCer: Synthesis and evaluation for iNKT cell stimulation Synthesis and Biological Activities of 5-Thio-α-GalCers Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation The 3-Deoxy Analogue of α-GalCer: Disclosing the Role of the 4-Hydroxyl Group for CD1d-Mediated NKT Cell Activation Synthesis and evaluation of 3″- and 4″-deoxy and -fluoro analogs of the immunostimulatory glycolipid, KRN7000 3-Fluoro- and 3,3-Difluoro-3,4-dideoxy-KRN7000 Analogues as New Potent Immunostimulator Agents: Total Synthesis and Biological Evaluation in Human Invariant Natural Killer T Cells and Mice Synthesis and biological activity of α-l-fucosyl ceramides, analogues of the potent agonist, α-d-galactosyl ceramide KRN7000 Synthesis and Biological Evaluation of α-Galactosylceramide Analogues with Heteroaromatic Rings and Varying Positions of a Phenyl Group in the Sphingosine Backbone Syntheses of Biotinylated α-Galactosylceramides and Their Effects on the Immune System and CD1 Molecules