Dihydropyrazolopyrimidine Inhibitors of KV1.5 (IKur)

Dihydropyrazolopyrimidine Inhibitors of KV1.5 (IKur) Design, synthesis and biological activity of pyrazolo[1,5-a]pyrimidin-7(4H)-ones as novel Kv7/KCNQ potassium channel activators Discovery of potent T-type calcium channel blocker A Rational Design of a Selective Inhibitor for Kv1.1 Channels Prevalent in Demyelinated Nerves That Improves Their Impaired Axonal Conduction Synthesis and biological activity of 3,4-dihydroquinazolines for selective T-type Ca2+ channel blockers Optimization of a Dihydropyrrolopyrazole Series of Transforming Growth Factor-β Type I Receptor Kinase Domain Inhibitors: Discovery of an Orally Bioavailable Transforming Growth Factor-β Receptor Type I Inhibitor as Antitumor Agent Structure–activity relationship exploration of Kv1.3 blockers based on diphenoxylate Dihydropyrimidine calcium channel blockers 51: bicyclic dihydropyrimidines as potent mimics of dihydropyridines 3,4-Dihydroquinazoline derivatives as novel selective T-type Ca2+ channel blockers Angular Methoxy-Substituted Furo- and Pyranoquinolinones as Blockers of the Voltage-Gated Potassium Channel Kv1.3