Characterization of Novel Selective H₁-Antihistamines for Clinical Evaluation in the Treatment of Insomnia

Characterization of Novel Selective H₁-Antihistamines for Clinical Evaluation in the Treatment of Insomnia Identification of a novel selective H1-antihistamine with optimized pharmacokinetic properties for clinical evaluation in the treatment of insomnia Benzo- and pyrido-1,4-oxazepin-5-ones and -thiones: synthesis and structure-activity relationships of a new series of H1-antihistamines Design, synthesis and biological activity evaluation of desloratadine analogues as H1 receptor antagonists Norpiperidine Imidazoazepines as a New Class of Potent, Selective, and Nonsedative H₁ Antihistamines Structure−Activity Relationships of Dimethindene Derivatives as New M₂-Selective Muscarinic Receptor Antagonists Synthesis and Structure−Activity Relationships of Novel Histamine H₁ Antagonists:  Indolylpiperidinyl Benzoic Acid Derivatives Synthesis and antihistamine evaluations of novel loratadine analogues New Antihistaminic Theophylline or Theobromine Derivatives Cardiotonic agents. 6. Histamine analogs as potential cardiovascular selective H2 agonists