Simocyclinone D8 turns on against Gram-negative bacteria in a clinical setting

Simocyclinone D8 turns on against Gram-negative bacteria in a clinical setting In Vivo and In Vitro Patterns of the Activity of Simocyclinone D8, an Angucyclinone Antibiotic from <i>Streptomyces antibioticus</i> Inhibition of Human Topoisomerases I and II by Simocyclinone D8 Comparison of In Vitro Activities of Fluoroquinolone-Like 2,4- and 1,3-Diones In Vitro Studies with DQ-113 and Comparison Fluoroquinolones To Determine Propensities To Select Resistance in Gram-Positive Cocci Gramicidin S-inspired antimicrobial cyclodextrin to disrupt gram-negative and gram-positive bacterial membranes U-87947E, a protein quinolone antibacterial agent incorporating a bicyclo[1.1.1]pent-1-yl (BCP) subunit In Vitro Activity of Nemonoxacin, a Novel Nonfluorinated Quinolone, against 2,440 Clinical Isolates A natural product inspired fragment-based approach towards the development of novel anti-bacterial agents Comparative In Vitro Activities of Nemonoxacin (TG-873870), a Novel Nonfluorinated Quinolone, and Other Quinolones against Clinical Isolates