Synthesis and opioid activity of novel 6-substituted-6-demethoxy-ethenomorphinans

Synthesis and opioid activity of novel 6-substituted-6-demethoxy-ethenomorphinans Analgesics of the 6,14-ethenomorphinan type. 6-Deoxy-7.alpha.-orvinol and 6-deoxy-8.alpha.-orvinol Synthesis and Biological Evaluation of 14-Alkoxymorphinans. 22. Influence of the 14-Alkoxy Group and the Substitution in Position 5 in 14-Alkoxymorphinan-6-ones on in Vitro and in Vivo Activities Synthesis, Pharmacology, and Molecular Docking Studies on 6-Desoxo-N-methylmorphinans as Potent μ-Opioid Receptor Agonists Analgesics of the orvinol type. 19-Deoxy and 6,20-epoxy derivatives Effect of a 6-Cyano Substituent in 14-OxygenatedN-Methylmorphinans on Opioid Receptor Binding and Antinociceptive Potency Synthesis and Biological Evaluation of 14-Alkoxymorphinans. 18. N-Substituted 14-Phenylpropyloxymorphinan-6-ones with Unanticipated Agonist Properties:  Extending the Scope of Common Structure−Activity Relationships N-Phenethyl Substitution in 14-Methoxy-N-methylmorphinan-6-ones Turns Selective µ Opioid Receptor Ligands into Dual µ/δ Opioid Receptor Agonists Novel 6β-acylaminomorphinans with analgesic activity Synthesis and Pharmacological Activities of 6-Glycine Substituted 14-Phenylpropoxymorphinans, a Novel Class of Opioids with High Opioid Receptor Affinities and Antinociceptive Potencies