Activity of Daptomycin against Listeria monocytogenes Isolates from Cerebrospinal Fluid

Antimicrobial Agents and Chemotherapy
2008.0

Abstract

We tested the activity of daptomycin against 76 Listeria monocytogenes isolates from cerebrospinal fluid by broth dilution and Etest methods. For the broth dilution method, the MIC range was 1.0 to 8.0 and the MIC at which 90% of the isolates tested were inhibited (MIC(90)) was 4.0 mg/liter. For the Etest method, the MIC range was 1.0 to 4.0 and the MIC(90) was 4.0 mg/liter. Presently, daptomycin cannot be recommended for the treatment of L. monocytogenes meningitis.

Knowledge Graph

Similar Paper

Activity of Daptomycin against Listeria monocytogenes Isolates from Cerebrospinal Fluid
Antimicrobial Agents and Chemotherapy 2008.0
Daptomycin Susceptibility of Unusual Gram-Positive Bacteria: Comparison of Results Obtained by the Etest and the Broth Microdilution Method
Antimicrobial Agents and Chemotherapy 2007.0
Daptomycin Produces an Enhanced Bactericidal Activity Compared to Ceftriaxone, Measured by [ <sup>3</sup> H]Choline Release in the Cerebrospinal Fluid, in Experimental Meningitis Due to a Penicillin-Resistant Pneumococcal Strain without Lysing Its Cell Wall
Antimicrobial Agents and Chemotherapy 2007.0
Activity of Daptomycin Alone and in Combination with Rifampin and Gentamicin against Staphylococcus aureus Assessed by Time-Kill Methodology
Antimicrobial Agents and Chemotherapy 2007.0
Nine-Hospital Study Comparing Broth Microdilution and Etest Method Results for Vancomycin and Daptomycin against Methicillin-Resistant Staphylococcus aureus
Antimicrobial Agents and Chemotherapy 2009.0
Activities of Daptomycin and Comparative Antimicrobials, Singly and in Combination, against Extracellular and Intracellular Staphylococcus aureus and Its Stable Small-Colony Variant in Human Monocyte-Derived Macrophages and in Broth
Antimicrobial Agents and Chemotherapy 2008.0
Attenuation of Cerebrospinal Fluid Inflammation by the Nonbacteriolytic Antibiotic Daptomycin versus That by Ceftriaxone in Experimental Pneumococcal Meningitis
Antimicrobial Agents and Chemotherapy 2010.0
Antimicrobial Activities of Daptomycin, Vancomycin, and Oxacillin in Human Monocytes and of Daptomycin in Combination with Gentamicin and/or Rifampin in Human Monocytes and in Broth against Staphylococcus aureus
Antimicrobial Agents and Chemotherapy 2007.0
Efficacy of Daptomycin against Bacillus anthracis in a Murine Model of Anthrax Spore Inhalation
Antimicrobial Agents and Chemotherapy 2010.0
Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes
Antimicrobial Agents and Chemotherapy 2008.0