Design and synthesis of macrocyclic indoles targeting blood coagulation cascade Factor XIa

Design and synthesis of macrocyclic indoles targeting blood coagulation cascade Factor XIa Clavatadine A, A Natural Product with Selective Recognition and Irreversible Inhibition of Factor XIa Engineering the Cyclization Loop of MCoTI-II Generates Targeted Cyclotides that Potently Inhibit Factor XIIa Design and Synthesis of Potent and Highly Selective Thrombin Inhibitors Factor XIIIa inhibitors as potential novel drugs for venous thromboembolism PRO_SELECT:  Combining Structure-Based Drug Design and Array-Based Chemistry for Rapid Lead Discovery. 2. The Development of a Series of Highly Potent and Selective Factor Xa Inhibitors Discovery of Phenylglycine Lactams as Potent Neutral Factor VIIa Inhibitors Dysinosins B−D, Inhibitors of Factor VIIa and Thrombin from the Australian Sponge<i>Lamellodysidea</i><i>c</i><i>hlorea</i> Dysinosins B−D, Inhibitors of Factor VIIa and Thrombin from the Australian Sponge<i>Lamellodysidea</i><i>c</i><i>hlorea</i> From natural products to achiral drug prototypes: Potent thrombin inhibitors based on P2/P3 dihydropyrid-2-one core motifs