Identification of novel ASK1 inhibitors using virtual screening

Identification of novel ASK1 inhibitors using virtual screening Discovery of a 2-pyridinyl urea-containing compound YD57 as a potent inhibitor of apoptosis signal-regulating kinase 1 (ASK1) Discovery of 2-arylquinazoline derivatives as a new class of ASK1 inhibitors New inhibitor of 3-phosphoinositide dependent protein kinase-1 identified from virtual screening Discovery of a novel protein kinase B inhibitor by structure-based virtual screening Virtual screening and further development of novel ALK inhibitors Design, synthesis, and discovery of novel non-peptide inhibitor of Caspase-3 using ligand based and structure based virtual screening approach Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAP-K2) as an Antiinflammatory Target: Discovery and in Vivo Activity of Selective Pyrazolo[1,5-a]pyrimidine Inhibitors Using a Focused Library and Structure-Based Optimization Approach Discovery of novel sphingosine kinase 1 inhibitorsvia structure-based hierarchical virtual screening Development of a novel fluorescent probe for fluorescence correlation spectroscopic detection of kinase inhibitors