Synthesis and biological evaluation of truncated α-galactosylceramide derivatives focusing on cytokine induction profile

Synthesis and biological evaluation of truncated α-galactosylceramide derivatives focusing on cytokine induction profile Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation Synthesis and Evaluation of 1,2,3-Triazole Containing Analogues of the Immunostimulant α-GalCer Synthesis and Biological Evaluation of α-Galactosylceramide Analogues with Heteroaromatic Rings and Varying Positions of a Phenyl Group in the Sphingosine Backbone Heteroaromatic Moieties in the Sphingosine Backbone of α-Galactosylceramides for Noncovalent Interactions with CD1d Efficient Divergent Synthesis of New Immunostimulant 4″-Modified α-Galactosylceramide Analogues Improved Th17 Selectivity of α-Galactosylceramide via Noncovalent Interactions with Diether Moiety Minimum structure requirement of immunomodulatory glycolipids for predominant Th2 cytokine induction and the discovery of non-linear phytosphingosine analogs Synthesis and biological activities of amino acids functionalized α-GalCer analogues Design, Synthesis, and Immunological Evaluation of Benzyloxyalkyl-Substituted 1,2,3-Triazolyl α-GalCer Analogues