Discovery of 3,4-Dihydropyrimidin-2(1H)-ones As a Novel Class of Potent and Selective A_2BAdenosine Receptor Antagonists

Discovery of 3,4-Dihydropyrimidin-2(1H)-ones As a Novel Class of Potent and Selective A_2BAdenosine Receptor Antagonists Discovery of Potent and Highly Selective A_2BAdenosine Receptor Antagonist Chemotypes 3,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A_2B Adenosine Receptor: Optimization, Structure–Activity Relationship Studies, and Enantiospecific Recognition Enantiospecific Recognition at the A_2BAdenosine Receptor by Alkyl 2-Cyanoimino-4-substituted-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxylates Discovery of benzothiazole-based adenosine A2B receptor antagonists with improved A2A selectivity Novel non-xanthine antagonist of the A2B adenosine receptor: From HTS hit to lead structure Trifluorinated Pyrimidine-Based A_2B Antagonists: Optimization and Evidence of Stereospecific Recognition 4-Substituted-7-N-alkyl-N-acetyl 2-aminobenzothiazole amides: Drug-like and non-xanthine based A2B adenosine receptor antagonists Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A₁ Antagonists Selective α1a adrenergic receptor antagonists based on 4-aryl-3,4-dihydropyridine-2-ones