Structure of the σ₁ Receptor and Its Ligand Binding Site

Structure of the σ₁ Receptor and Its Ligand Binding Site Homology Model and Docking-Based Virtual Screening for Ligands of the σ₁ Receptor Structural Features Important for .sigma.1 Receptor Binding Identification, pharmacological evaluation and binding mode analysis of novel chromene and chromane based σ1 receptor ligands Synthesis and binding assays of novel 3,3-dimethylpiperidine derivatives with various lipophilicities as σ1 receptor ligands From α4β2 Nicotinic Ligands to the Discovery of σ1 Receptor Ligands: Pharmacophore Analysis and Rational Design 1‘-Benzyl-3,4-dihydrospiro[2H-1- benzothiopyran-2,4‘-piperidine] (Spipethiane), a Potent and Highly Selective σ₁ Ligand Design and Synthesis of Photoaffinity-Labeling Ligands of the<scp>l</scp>-Prolyl-<scp>l</scp>-leucylglycinamide Binding Site Involved in the Allosteric Modulation of the Dopamine Receptor Synthesis and Structure–Affinity Relationships of Spirocyclic Benzopyrans with Exocyclic Amino Moiety Enantiomerically Pure 1,3-Dioxanes as Highly Selective NMDA and σ₁Receptor Ligands