Synthesis of quinazoline analogs of folic acid modified at position 10

Synthesis of quinazoline analogs of folic acid modified at position 10 Comparison of the biological effects of selected 5,8-dideazafolate analogs with their 2-desamino counterparts Quinazolines as inhibitors of dihydrofolate reductase. 4. Classical analogs of folic and isofolic acids Folate analogs as inhibitors of thymidylate synthase Folate analogs. 21. Synthesis and antifolate and antitumor activities of N10-(cyanomethyl)-5,8-dideazafolic acid Synthesis and antitumor activity of 5-deaza-5,6,7,8-tetrahydrofolic acid and its N10-substituted analogs Synthesis of 5-chloro-5,8-dideaza analogs of folic acid and aminopterin targeted for colon adenocarcinoma Chemistry and antitumor evaluation of selected classical 2,4-diaminoquinazoline analogs of folic acid Synthesis and biological evaluation of 8-deazahomofolic acid and its tetrahydro derivative Folate analogs. 35. Synthesis and biological evaluation of 1-deaza, 3-deaza, and bridge-elongated analogs of N10-propargyl-5,8-dideazafolic acid