5-Chloro-2-phenyl-1-benzo[b]thiophene-3-alkanamines, potential antipsychotic agents

Journal of Medicinal Chemistry
1978.0

Abstract

The title compounds (most notably 2a) were synthesized on the basis of the N-methylation hypothesis of schizophrenia. They were evaluated in dopamine and haloperidol receptor assays. The binding characteristics were comparable in some cases to known neuroleptics.

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