Microbial conversion of .EPSILON.-pyrromycinone and .EPSILON.-isorhodomycinone to 1-hydroxy-13-dihydrodaunomycin and n-formyl-1-hydroxy-13-dihydrodaunomycin and their bioactivities.

Microbial conversion of .EPSILON.-pyrromycinone and .EPSILON.-isorhodomycinone to 1-hydroxy-13-dihydrodaunomycin and n-formyl-1-hydroxy-13-dihydrodaunomycin and their bioactivities. Microbial conversion of anthracyclinones to daunomycin by blocked mutants of Streptomyces coeruleorubidus. Microbial conversion of anthracyclinones to daunomycin by blocked mutants of Streptomyces coeruleorubidus. Biosynthesis of daunomycinone from aklavinone and .EPSILON.-rhodomycinone. Production of new anthracycline antibiotics 1-hydroxyoxaunomycin and 6-deoxyoxaunomycine by limited biosynthetic conversion using a daunorubicin-negative mutant. Biotransformations of anthracyclinones inStreptomyces coeruleorubidus andStreptomyces galilaeus New anthracyclines, feudomycins, produced by the mutant from Streptomyces coeruleorubidus ME130-A4. Biosynthesis of daunorubicin glycosides: role of epsilon-rhodomycinone Intensely potent anthracycline antibiotic oxaunomycin produced by a blocked mutant of the daunorubicin-producing microorganism. Isolation and characterization of stable mutants ofStreptomyces peucetius defective in daunorubicin biosynthesis