From the herb Stephania hernandifolia (family Menispermaceae) growing in Transcaucasia, a base with the composition C₂₀H₂₇O₅N was isolated via its sparingly soluble hydrochloride. Its physical constants (mp 114-115 °C from ether, 144.5 °C from methanol; [α]ᴰ -97.9° (c 0.7, ethanol); mol wt 370 (Rast); hydrochloride mp 199.5-200.5 °C from ethanol), functional groups (three OCH₃, two OH, one NCH₃ groups), and spectral data (IR: 3300, 3520, 1590, 1630 cm⁻¹; UV: λmax 216, 285 nm with log ε 3.94, 3.48) were characterized, and it was identified as a new alkaloid. Hofmann degradation yielded a methiodide (mp 178-180 °C) and a desbase (mp 114-115 °C) which showed no mp depression and same TLC Rf as the desbase of hernandoline. Acetolysis of the desbase formed a substance (mp 163-164 °C) identical to diacetoxydimethoxyphenantrene from hernandoline. Comparison with the product of hernandoline reduced by sodium borohydride revealed similar composition, constants, and identical IR spectra. Based on these findings, the alkaloid was named "hernandolinol" and structure I was proposed.