From the crude drug 'Ipecac' (dried root of Cephaelis ipecocuunhu) six novel tetrahydroisoquinolinemonoterpene glucosides, 6-0-methylipecoside, ipecosidic acid, demethylalangiside, neoipecoside, 7-O-methylneoipecoside and 3,4_dehydroneoipecoside were isolated along with ipecoside, alangiside. sweroside and 7-dehydrologanin. The structures of new glucosides were determined by spectroscopic and chemical means. The biogenesis of these glucosides is also discussed.