The Isolation of strychnine and brucme from seeds of Strychnos panamensu Seem from Guatemala, Central Amerrca, IS reported The alkaloids, 0 1% of each, were found only m those seeds which were mature and capable of germmatlon, immature and overmature seeds were not found to contam either of the two bases This 1s the iirst time that strychmne and brucme have been ldenttied wth certainty m an Amencan species of Strychnos Together with the results of previous work, S panamensis has now been shown to contain alkaloids of the strychnine, dlabohne, and bls-quatemary types