Alkaloids ofAllium

Chemistry of Natural Compounds
1986.0

Abstract

Plants of the genus Allium were previously considered not alkaloid-bearing, but alkaloids were found in some species. This study investigated two Allium species: A. senescens (collected in the environs of Vakhmistrovo, Ulan-Ude region, Buryat ASSR on July 25, 1983) and A. anisopodium (collected in the environs of Ulan-Ude on July 7, 1983). The dried comminuted epigeal part (1 kg) and bulbs (0.5 kg) of A. senescens were extracted with 80% ethanol, evaporated in vacuum to semiviscous state, dissolved in 5% sulfuric acid, washed with ether, alkalized with 20% sodium carbonate, and extracted with chloroform, yielding 0.13% (epigeal part) and 0.10% (bulbs) of combined alkaloids (on dry raw material weight). 1.3 g of combined alkaloids from A. senescens' epigeal part was separated on a silica gel column with chloroform-methanol (10:1) eluate, obtaining an alkaloid (mp 91-92°C) identified as alline by Rf, mixed melting point, and IR spectra. From the epigeal part of A. anisopodium (1.5 kg), 2.57 g (0.17%) of combined alkaloids were obtained, and alline was isolated via chromatography. Thus, alline was obtained for the first time from A. senescens and A. anisopodium.

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