Alkaloids from Annona cherimolia Leaves

Journal of Natural Products
1985.0

Abstract

In a previous work, the isolation of alkaloids from Annona cherimolia Mill. (Annonaceae) seeds (1) and twigs (2) was reported. In the present paper, we have isolated and identified eight alkaloids from the leaves. (+)-Isoboldine, (-)-stepholidine, (+)-corytuberine and (+)-nornamenine have been reported for the first time from this source. (+)-Retidine, (-)-anonaine, liriodenine, and lanuginosine were identified from seeds and twigs. Michelalbine, detected previously in A. cherimolia twigs (2), has not been detected in the leaves. In our continuing study of the medicinal plants of northeastern Brazil, we investigated the stem-bark of Zizyphus joazeiro Mart. from which we report here the isolation of betulinic acid, oleanolic acid, and a saponin which furnished ebilin lactone (1) upon acid hydrolysis. Ebilin lactone is certainly an artifact arising from the acid hydrolysis of the saponin which, like jujuboside A, jujuboside B, hovenoside, and bacoside A, is probably a glycoside of jujubogenin (1.2) because, the saponin neither showed the characteristic uv absorption for a conjugated triene nor the strong ir band of y-lactone shown by ebilin lactone.

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