From the bulbs of vietnamese Hippeastrum equestre Herb. (Amaryllidaceae), two novel Amaryllidaceae alkaloids 3-O-demethyltazettine and egonine have been isolated. Their structures were established by spectroscopic analysis (UV, MS, NMR and CD) as well as by comparison with respective spectroscopic data of tazettine and tazettadiol. (C) 1999 Elsevier Science Ltd. All rights reserved.