Alkaloids of the epigeal organs ofHippeastrum equestre

Chemistry of Natural Compounds
1982.0

Abstract

From the epigeal organs of Hippeastrum equestre Herb. (family Amaryllidaceae) collected in the Peoples' Republic of Bangladesh during the flowering period, total bases were obtained by chloroform extraction. Based on solubility differences in organic solvents, 2.36 g of lycorine, 0.30 g of galanthine, and 0.28 g of galanthamine were isolated. Chromatography of the residual material on a KSK silica gel column using chloroform-methanol mixtures with successive increases in methanol concentration yielded 0.54 g of hippeastrine, 0.76 g of tazettine, 0.40 g of hemanthamine, and 0.32 g of a base (III) with mp 243--245°C (decomp, methanol). The compounds were identified via determination of physicochemical constants, thin-layer chromatography, and UV, NMR, and mass spectroscopy. This is the first time any of the mentioned alkaloids have been isolated from the epigeal organs of Hippeastrum equestre.

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