5_Methyldihydroflavasperone, a novel naphthopyran, was isolated from the chloroform extract of the leaf of Guiera senegalensis. The structure was established as 2,3-dihydro-5,8,10-trimethoxy-2-methyl-4H-naphtho[l,Zb]pyran-Cone by 1D and 2D NMR spectroscopy (H-H COSY; H-C COSY, DEPT; INADEQUATE) and other spectroscopical techniques.