Seven flavonoids, including one new flavonol, were isolated from the leaves of Murraya paniculata (Rutaceae). Four were identified as previously known constituents of M. paniculata or allied species, namely, 5,7,3',4',5'-pentamethoxyflavone, 5,7,8,3',4',5'-hexamethoxyflavone, 3,5,7,3',4',5'-hexamethoxyflavone and 3,5,7,8,3',4',5'-heptamethoxyflavone. The structure of the new flavonol was elucidated as 3-hydroxy-5,7,3',4',5' pentamethoxyflavone on the basis of spectroscopic studies. Two other flavonoids, a methylated flavanone and its corresponding chalcone isomer were identified as 2-(S)-5,7,3',4',5'-pentamethoxyflavanone and 2'-hydroxy-3,4,5,4',6'-pentamethoxychalcone, respectively.