20-Ketoreductase Activity of Chaetoglobosin A and Prochaetoglobosins in a Cell-free System ofChaetomium subaffineand the Isolation of New Chaetoglobosins

20-Ketoreductase Activity of Chaetoglobosin A and Prochaetoglobosins in a Cell-free System of<i>Chaetomium subaffine</i>and the Isolation of New Chaetoglobosins Useful approach to find the plausible biosynthetic precursors of secondary metabolites using P-450 inhibitors: postulated intermediates of chaetoglobosin A 19‐<i>O</i>‐Acetylchaetoglobosin B and 19‐<i>O</i>‐Acetylchaetoglobosin D, Two New Metabolites of <i>Chaetomium globosum</i> Chaetoglobosins Q, R, and T, Three Further New Metabolites from <i>Chaetomium </i><i>g</i><i>lobosum</i> Chaetoglobosins Q, R, and T, Three Further New Metabolites from <i>Chaetomium </i><i>g</i><i>lobosum</i> Structures of chaetoglobosins C, D, E, and F, cytotoxic indol-3-yl-[13]cytochalasans from Chaetomium globosum New plausible precursors of chaetoglobosin a accumulated by treatment of chaetomium subaffine with cytochrome P-450 inhibitors Cytotoxic Chaetoglobosins from the Endophyte<i>Chaetomium globosum</i> Aureochaeglobosins A–C, Three [4 + 2] Adducts of Chaetoglobosin and Aureonitol Derivatives from <i>Chaetomium globosum</i> Cytotoxic Chaetoglobosins from the EndophyteChaetomium globosum