<jats:title>Abstract</jats:title><jats:p>Two novel alkaloids, 4,5‐dihydroxy‐1‐methyl‐3‐oxo‐2‐(trichloromethyl)‐3<jats:italic>H</jats:italic>‐indolium chloride (<jats:bold>1</jats:bold>) and 4‐(2‐methoxyethyl)‐<jats:italic>N</jats:italic>,<jats:italic>N</jats:italic>‐dimethylbenzenamine (<jats:bold>2</jats:bold>), were isolated from the EtOH extract of the roots of <jats:italic>Zanthoxylum nitidum.</jats:italic> Their structures were identified on the basis of spectroscopic and mass‐spectrometric analyses.