Two novel alkaloids, 4,5-dihydroxy-1-methyl-3-oxo-2-(trichloromethyl)-3H-indolium chloride (1) and 4-(2-methoxyethyl)-N,N-dimethylbenzenamine (2), were isolated from the EtOH extract of the roots of Zanthoxylum nitidum. Their structures were identified on the basis of spectroscopic and mass-spectrometric analyses.