The EtOH extract of dried root bark of Tripterygium wilfordii HooK, v, (Cetastraceae) afforded a novel macrolactone cyclopeptide named triptotin L (= cyclo[L-alanyl-L-alanyl-3-(4,4,9-trimethyldecyl-3-hydroxypropanoylglcyl-L-valyl-L-leucyl;: 1), the new triterpene 2beta,6alpha,22beta-trihydroxy-24,29-dinor-D : A-friedoolean-4-ene-3,21-dione named 6alpha-hydroxytriptocalline A (=(2beta,6alpha,8alpha,9beta,10alpha,13alpha,14beta,20beta,22beta)-2,6,22-trihydroxy-9,13-dimethyl-24.25,26,30-tetranorolean-4-ene-3,21-dione 2), the new diterpenoid 11,16-dihydroxy-14-methoxy-18(4-->3) abeo-abieta-3.8,11,13-tetraene-18-oic acid named 16-hydroxytriptobenzene H (=(4aS,10aS)-3,4.4a,9,10,10a-hexahydro-5-hydrox-7-(2-hydroxy-l-metthylethyl)-8-methoxy-1,4a-dimethylphenanthrene-2-carboxy acid; 3). and the abietane diterpenoid alkaloid named triptotin J (=(7aS,11aS,11bS)-7,7a.8.9,10,11,11a,11b-octahydro-11b-hydroxy-alpha,alpha,8,8,11a-pentamethyl-6ll-naphth[1,2-d]azepine-4-methanol: 4).Their structures were established on the basis of spectroscopic studies.