A new amide, magnolamide (1), and a new lignan, magnolone (2), whose structures were determined on the basis of spectral analysis, were found in the leaves of Magnolia coco. Eleven known compounds (episesamin, sesamin, magnolol, fargesin, aschantin, epieudesmin, syringaresinol, syringaresinol-O-beta-D-glucopyroside, scoparone, oxoanolobine, and dicentrinone) were also isolated.