<jats:title>Abstract</jats:title><jats:p>Eighteen compounds including fourteen lignans, one coumarin, and three alkaloids were isolated from the leaves of <jats:italic>Magnolia coco.</jats:italic> Their structures were established by comparison of spectral data with literature values. Among them, <jats:italic>N</jats:italic>‐acetylanolobine was elucidated as a new compound.