PRODUCTION OF TREMORGENIC TOXINS BY PENICILLIUM JANTHINELLUM BIOURGE: A POSSIBLE AETIOLOGICAL FACTOR IN RYEGRASS STAGGERS

Australian Journal of Experimental Biology and Medical Science
1979.0

Abstract

<jats:title>Summary</jats:title><jats:p>Topsoil herbage and faces collected during an outbreak of ryegrass staggers in sheep were examined for tremorgenic peniecllia. No such fungi were recovered from the plant material, but they were found among the predominant fungi in the soil and faecal samples. The commonest species of <jats:italic>Penicillium</jats:italic> and almost the only tremorgenic species encountered, was <jats:italic>Penicillium Janthinellum</jats:italic> Biourge. When fed to sheep, the mycelium of this fungus evoked a number of the clinical signs seen in field eases of ryegrass staggers. Two tremorgenic toxins were isolated from the mycelial felts and available evidence indicates that they are verruculogen and funitremorgin A. P. janthinethum also produced these tremorgens when from this study are in accord with the hypothesis that ryegrass staggers is caused by tremorgenic mycotoxins.

Knowledge Graph

Similar Paper

PRODUCTION OF TREMORGENIC TOXINS BY <i>PENICILLIUM JANTHINELLUM</i> BIOURGE: A POSSIBLE AETIOLOGICAL FACTOR IN RYEGRASS STAGGERS
Australian Journal of Experimental Biology and Medical Science 1979.0
FUNGAL TREMORGENS ASSOCIATED WITH RYEGRASS STAGGERS IN SOUTH AUSTRALIA
Australian Veterinary Journal 1979.0
Structure elucidation of the janthitrems, novel tremorgenic mycotoxins from Penicillium janthinellum
Journal of the Chemical Society, Perkin Transactions 1 1984.0
Chemically Different Tremorgenic Mycotoxins in Isolates of Penicillium paxilli From Australia and North America
Journal of Natural Products 1979.0
Janthitrems B and C, two principal indole-diterpenoids produced by Penicillium janthinellum
Phytochemistry 1993.0
Studies on fungal products. Part XXXIII. Structures of new indoloditerpenes, possible biosynthetic precursors of the tremorgenic mycotoxins, penitrems, from Penicillium crustosum.
Chemical and Pharmaceutical Bulletin 1990.0
Identification and Structure Elucidation of Janthitrems A and D from <i>Penicillium janthinellum</i> and Determination of the Tremorgenic and Anti-Insect Activity of Janthitrems A and B
Journal of Agricultural and Food Chemistry 2018.0
In Vitro Effects of Tremorgenic Mycotoxins
Journal of Natural Products 1991.0
Paspalum staggers: isolation and identification of tremorgenic metabolites from sclerotia of Claviceps paspali
Journal of Agricultural and Food Chemistry 1977.0
Lolitrems, peramine and paxilline: Mycotoxins of the ryegrass/endophyte interaction
Agriculture, Ecosystems &amp; Environment 1993.0