Furoquinoline Alkaloids of Teclea ouabanguiensis

Journal of Natural Products
1982.0

Abstract

From the stem bark of Teclea ouabanguiensis Aubrev. & Perr. (Rutaceae), six furoquinoline alkaloids have been isolated and characterized. Previously known alkaloids, but new to this plant, were tecleaverdoornine (l), tecleine (3), flindersiamine (4), montrifoline (nkolbisine) (5) and kokusaginine (6), while tecleamine 2 is reported from a natural source for the first time. Spectroscopic and chemical evidence is presented for the structure of the new isolate 2. In previous papers we have reported the structure determination of new prenylated furoquinoline alkaloids and tetranortriterpenoids (limonoids) isolated from three species of the genus Teclea Delile (Rutaceae): T. aerdoorniana (1, 2, 3), T. grandifoh (4), and T. ufzelii (5). The interesting chemical structures of these products prompted us to investigate other species of the same genus. This paper deals with the results obtained from the chemical examination of a previously uninvestigated endemic Cameroonian species, Teclea ouabanguiensis Aubrev. & Perr. (6, 7).

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