Taxanes from the roots of Taxus mairei

Phytochemistry
1997.0

Abstract

Extensive column chromatography of the ethanolic extracts from the roots of Taxus mairei and subsequent purification of taxanes by HPLC gave two derivatives of baccatin I and one derivative of taxchin. The structural assignments of the taxoids were based on their spectral data, including 2D NMR experiments and chemical correlation. X-ray crystallographic analysis of 1β-hydroxybaccatin I provided unambiguous characterization for the structures and relative stereochemistries of the other taxanes.

Knowledge Graph

Similar Paper