<jats:p>Twenty one alkaloids were isolated from the leaves of <jats:italic>Buxus sempervirens</jats:italic> var <jats:italic>rotundifolia</jats:italic> BAILLON. Buxaminol-B, cyclobuxine-D, cyclovirobuxine-D, cycloprotobuxine-C, buxamine-E, buxtauine-M and buxpiine-K were those already known. New alkaloids, the constitution and configuration of which were inferred from physical data and corroborated by interconversion and correlation, were denominated buxithienine-M and cyclobuxophylline-O. The remaining bases were characterized by physico-chemical constant and/or spectral data.