Chemical constituents of tropical plants. 11. Stereostructures of neurolenins A and B, novel germacranolide sesquiterpenes from Neurolaena lobata (L.) R.Br

The Journal of Organic Chemistry
1978.0

Abstract

Two novel germacranolide sesquiterpenoids, neurolenins A (4) and B (5), have been isolated from Neurolaena lobata (L.) R.Br. (Compositae) and their stereostructures determined from spectral and X-ray crystallographic analyses; 4 and 5 possessed the α-methylene-γ-butyrolactone moiety, but were inactive against sarcoma-180 in rats.

DOI： 10.1021/jo00416a020

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