STRUCTURE ELUCIDATION OF MACROCYCLIC LACTONE ANTIBIOTICS, MBA 028-24 A AND B

Analytical Sciences
1991.0

Abstract

The structures of antibiotics MBA 028-24 A and B produced by Streptomyces hyroscopicus A1491 were elucidated from the pysico chemical properties, 2D-NMR techniques and chemical degradation experiments. These antibiotics consist of a 36-membered polyhydroxy lactone ring, a guanidino group and a monoester of malonic acid.

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