Alkaloids of Vinca rosea Linn. (Catharanthus roseus G. Don.) VIII

Journal of Pharmaceutical Sciences
1961.0

Abstract

Continuation of the phytochemical examination of this plant (1) which has produced two antitumor principles, vincaleukoblastine and leurosine, has yielded six previously unreported minor alkaloids in addition to those already reported from these laboratories (2). Details of the procedure leading to the preparation of isoleurosine, lochneridine, sitsirikine sulfate, vincamicine, Catharine, and vindolicine, as well as their preliminary characterization, are described.

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