A study of the non quaternary alkaloids of roots, stems, leaves and fruits of Limaciopsis loangensis ENGL. (Menispermaceae), resulted in the isolation of thirteen alkaloids. The alkaloidal content is typical for a menispermaceous plant. Most of alkaloids are bisbenzyltetrahydroisoquinolines, specially of the berbamine type; isotetrandrine is the main alkaloid. Two new alkaloids have been isolated, 2'-nor-isotetrandrine and 2'-N-oxyisotetrandrine. An oxoaporphine and a protoberberine derivative are present.