A new 3-oxaquinolizidine alkaloid (3R*,4aR*,6S*, 8R*)-6-hydroxy-3-methyl-8-pentylperhydropyrido[1,2-c][1,3]oxazine 6-(pyrrole-2-carboxylate) (hyperaspine) has been isolated from the ladybird beetle Hyperaspis campestris ans its structure determined by 2D NMR and MS methods. (C) 2001 Elsevier Science Ltd. All rights reserved.