Total Synthesis of (+)-Gilbertine: A Cyclopentanone-Based Approach

Organic Letters
2022.0

Abstract

From methyl jasmonate, the concise asymmetric total synthesis of uleine alkaloid gilbertine was reported. The synthesis demonstrated the power of a cyclopentanone-based approach involving the coupling of 2-aminobenzaldehyde and diazo-cyclopentanone for the rapid assembly of the hydrocarbazole natural product. © 2022 American Chemical Society.

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