Cnidoscolus aconitifolius belonging to Euphorbiaceae family is widely used as a folk medicine among South American countries such as Mexico and Brazil. C. aconitifolius can be considered as a potential leafy green vegetable, largely due to the presence of various secondary metabolites. Different bioactive compounds such as phenolic acids, Alkaloids, saponins, flavonoids etc. along with terpenoids have unique structure that are exclusive for this genus. C. aconitifolius has numerous nutraceutical benefits proven with pharmacological studies such as anti-diabetic, hepatoprotective, antimicrobial etc. The recent upsurge of consumer interest for health promoting products has opened up new vistas for C. aconitifolius application in food product research and development field. Limited knowledge about this underutilized plant is presenting an opportunity to explore the plant as novel ingredient with vast functional attributes. © FFC 2021.