Two new alkaloids, glaucenamide (1) and fissiceine (2), along with fifteen known ones, liriodenine (3), oxocrebanine (4), kuafumine (5), oxoxylopine (6), atherospermidine (7), (-)-xylopine (8), (-)-N-acetylxylopine (9), N-trans-feruloyltyramine (10), aristololactam BII (11), aristololactam BIII (12), aristololactam AII (13), piperolactam A (14), goniothalactam (15), norcepharadion B (16), and noraristolodione (17) were isolated from the methanolic extracts of the Fissistigma glaucescens. The structures of these compounds were established by means of spectral analysis.