The following substances have been isolated from Haplophyllum robustum: from the epigeal part haplopine, and from the roots skimmianine, γ-fagarine, a new alkaloid robustine C11H5ON(OH)(OCH3), and a base with mp 230-231°. Robustine has the structure 4-methoxy-8-hydroxyfuro[2, 3-b]quinoline. © 1966 The Faraday Press, Inc.