Skimmianine, folimine, benzamide, and new alkaloid haplotusine (mp 118-119°C, C11H11NO3, M+ 205) have been isolated from the epigeal part of Haplophyllum obtusifolium Ledeb. growing in the environs of Kora-Koly, Turkmen SSR. By the analysis of spectral characteristics it has been established that haplotusine has the structure of 1,4-dimethoxy-2-quinolone. © 1985 Plenum Publishing Corporation.