Berberine, isocorydine, glaucine, thalicmidine, aromoline, oxyacanthine, and the new 1-benzylisoquinoline alkaloid turcomanine have been isolated from Berberis turcomanica Kar. The structure of the new alkaloid has been established on the basis of chemical transformations and spectral characteristics. This is the first time that isocorydine, thalicmidine, aromoline, and oxyacanthine have been isolated from this plant. ©1996 Plenum Publishing Corporation.