Berberine, magnoflorine, palmatine, columbamine, jatrorhizine, epiberberine, berbamine, O-methylisothalicberine, armepavine, corypalline, glaucine, and corydine and the new alkaloid turcberine have been isolated from Berberis turcomanica Kar., and the structure of turcberine has been established. Apart from berberine, this is the first time that any of these alkaloids have been isolated from this species of barberry, while this is the first time that corydine and armepavine have been isolated from the genus Berberis. © 1993 Plenum Publishing Corporation.