Kopsine, C22H26O4N2, the alkaloid of Kopsia fruticosa, on mild degradation with aqueous and alcoholic alkali produces two new bases—kopsidine, C20H24O3N2, m.p. 142° (dec.) and kopsidinine, C19H22O2N2, m.p. 248° (dec.), which is free from methoxy. Their isolation, analyses, properties and ultraviolet absorption curves have been described. Kopsine produces 2-methylindole, C9H9N, m.p. 57°; indole-2-carboxylic acid, C9H7O2N, m.p. 199°; and an uncharacterized base (in traces) on fusion with potassium hydroxide. © 1953, American Chemical Society. All rights reserved.